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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXK All Species: 16.67
Human Site: S183 Identified Species: 40.74
UniProt: P42681 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42681 NP_003319.2 527 61258 S183 R D S R H L G S Y T I S V F M
Chimpanzee Pan troglodytes XP_517311 461 53260 H118 I L E K Y N P H W W K A R D R
Rhesus Macaque Macaca mulatta XP_001103052 527 61170 S183 R D S R H L G S Y T I S V F I
Dog Lupus familis XP_539258 585 67628 S219 R D S R H L G S Y T I S V F I
Cat Felis silvestris
Mouse Mus musculus P42682 527 61090 S183 R D S R H L G S Y T I S V F T
Rat Rattus norvegicus Q07014 512 58642 V169 K G S F S L S V R D Y D P M H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515402 583 67167 T236 S S Q P G L Y T V S L Y T K F
Chicken Gallus gallus Q8JH64 657 75860 K312 D S T S K T G K Y T V S V Y A
Frog Xenopus laevis P13116 532 59718 T178 F L V R E S E T T K G A Y C L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08630 786 87374 T440 F V V R K S S T K G L Y T L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.7 96.9 78.9 N.A. 83.4 36.2 N.A. 51.1 45.2 36.6 N.A. N.A. 33.7 N.A. N.A. N.A.
Protein Similarity: 100 87 98.2 84.4 N.A. 92.4 56.1 N.A. 67.2 59.2 52.6 N.A. N.A. 45.9 N.A. N.A. N.A.
P-Site Identity: 100 0 93.3 93.3 N.A. 93.3 13.3 N.A. 6.6 33.3 6.6 N.A. N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 93.3 20 N.A. 26.6 53.3 26.6 N.A. N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 40 0 0 0 0 0 0 0 10 0 10 0 10 0 % D
% Glu: 0 0 10 0 10 0 10 0 0 0 0 0 0 0 0 % E
% Phe: 20 0 0 10 0 0 0 0 0 0 0 0 0 40 10 % F
% Gly: 0 10 0 0 10 0 50 0 0 10 10 0 0 0 0 % G
% His: 0 0 0 0 40 0 0 10 0 0 0 0 0 0 10 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 40 0 0 0 20 % I
% Lys: 10 0 0 10 20 0 0 10 10 10 10 0 0 10 0 % K
% Leu: 0 20 0 0 0 60 0 0 0 0 20 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 10 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 40 0 0 60 0 0 0 0 10 0 0 0 10 0 10 % R
% Ser: 10 20 50 10 10 20 20 40 0 10 0 50 0 0 10 % S
% Thr: 0 0 10 0 0 10 0 30 10 50 0 0 20 0 10 % T
% Val: 0 10 20 0 0 0 0 10 10 0 10 0 50 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 10 0 50 0 10 20 10 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _